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anti-mycobacterial activity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (9) Apoptosis (4) Autophagy (1) Bacterial (56) DNA/RNA Synthesis (1) Drug Metabolite (1) Fungal (4) HSP (1) Interleukin Related (1) Isotope-Labeled Compounds (2) Mitochondrial Metabolism (1) Oxidative Phosphorylation (1) Parasite (11) Potassium Channel (1) Reactive Oxygen Species (3)
By Research Areas:	Cancer (7) Infection (60) Inflammation/Immunology (14) Metabolic Disease (1) Neurological Disease (2)

Inhibitors & Agonists

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Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-151354

Antibacterial agent 121	Bacterial	Infection
Antibacterial agent 121 (Compound 10) is an antibacterial agent. Antibacterial agent 121 shows anti-mycobacterial and anti-inflammatory activities and can be used in Tuberculosis (TB) research .

HY-15993

Posizolid AZD2563; AZD5847	Antibiotic	Infection
Posizolid (AZD2563), an oxazolidinone antibiotic, is developed by AstraZeneca for the study of bacterial infections. Posizolid shows very good *anti-mycobacterial* activity .

HY-151205

Antituberculosis agent-3	Bacterial	Infection Inflammation/Immunology
Antituberculosis agent-3 (Compound 2) is an antituberculosis agent. Antituberculosis agent-3 shows anti-mycobacterial activity, and can inhibit M. tuberculosis H37Rv strain growth (MIC=12.5 μg/mL) .

HY-151204

PknB-IN-1	Bacterial	Infection Inflammation/Immunology
PknB-IN-1 (Compound 2) is a protein kinase B (PknB) inhibitor (IC₅₀=14.4 μM). PknB-IN-1 shows anti-mycobacterial activity, can inhibit M. tuberculosis H37Rv strain growth (MIC=6.2 μg/mL) .

HY-146158

WX-081	Bacterial Potassium Channel Antibiotic	Infection
WX-081, an anti-tuberculosis agent, displays excellent anti-mycobacterial activity against M. tuberculosis H37Rv and low cytotoxicity. WX-081 exhibits potent activity with MIC50s of 0.083 and 0.11 μg/mL for agent susceptible tuberculosis (DS-TB) and multidrug resistant tuberculosis (MDR-TB) strains. WX-081 also inhibits hERG channel with the IC50 of 1.89 μM.

HY-N8131

Pangelin

Bacterial Infection Cancer

Pangelin is a coumarin that can be found in Ducrosia anethifolia. Pangelin exhibits anti-mycobacterial and anti-tumor activities .

Pangelin	Bacterial	Infection Cancer
Pangelin is a coumarin that can be found in Ducrosia anethifolia. Pangelin exhibits anti-mycobacterial and anti-tumor activities .

HY-B1046

Clofazimine Maximum Cited Publications 6 Publications Verification	Bacterial Antibiotic DNA/RNA Synthesis Interleukin Related Apoptosis	Infection Inflammation/Immunology Cancer
Clofazimine is an orally-active anti-mycobacterial agent with a wide range of anti-mycobacterial activity including leprosy and tuberculosis. Clofazimine exerts anti-inflammatory activities and anti-tumor activities by interfering DNA replication and inhibiting IL2 (IC₅₀ = 1.10 ± 0.26 μM, Jurkat T) production. Clofazimine can be used in mycobacterial and cancer research .

HY-147704

Antimycobacterial agent-2	Bacterial	Infection
Antimycobacterial agent-2 (compound 58) is a potent antimycobacterial agent. Antimycobacterial agent-2 shows anti-mycobacterial activities with an MIC₉₉ of 0.8 µM for Mycobacterium tuberculosis (M.tb) H37Rv. Antimycobacterial agent-2 shows cytotoxic activities with an IC₅₀ of48.1 µM for CHO cells .

HY-151356

Antibacterial agent 122	Bacterial	Infection
Antibacterial agent 122 (compound 15) is a thiourea derivative with anti-mycobacterial activity and low cytotoxicity. Antibacterial agent 122 can be used for tuberculosis-related studies .

HY-109588

NITD-349 1 Publications Verification	Bacterial	Infection
NITD-349 is an MmpL3 inhibitor that shows highly potent anti-mycobacterial activity with MIC₅₀ of 23 nM against virulent Mycobacterium tuberculosis H37Rv.

HY-109587

BM635

Bacterial Infection

BM635 is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 has an MIC₅₀ of 0.12 μM against M. tuberculosis H37Rv.

BM635	Bacterial	Infection
BM635 is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 has an MIC₅₀ of 0.12 μM against M. tuberculosis H37Rv.

HY-N3845

Ergosterol peroxide	Bacterial	Inflammation/Immunology Cancer
Ergosterol peroxide is a steroid derivative and can be isolated from a variety of fungi, yeast, lichens or sponges. Ergosterol peroxide has anti-tumour, proapoptotic, anti-inflammatory, anti-mycobacterial, and anti-proliferative activities .

HY-109587B

BM635 mesylate	Bacterial	Infection
BM635 mesylate is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 mesylate has a MIC₅₀ of 0.6 μM against M. tuberculosis H37Rv. BM635 mesylate significantly improves the bioavailability compared to free-base BM635 .

HY-N2443

Tribuloside 1 Publications Verification	Bacterial	Infection Neurological Disease
Tribuloside is a flavonoid that can be isolated from Tribulus terrestris L . Tribuloside exhibits *anti-mycobacterial* activity against the non-pathogenic Mycobacterium species with a minimum inhibitory concentration (MIC) of 5.0 mg/mL. Tribuloside has 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity .

HY-109587A

BM635 hydrochloride	Bacterial	Infection
BM635 hydrochloride is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 hydrochloride has an MIC₅₀ of 0.08 μM against M.tuberculosis H37Rv. BM635 hydrochloride doubles the in vivo exposure with respect to the free base BM635 .

HY-N7030

5,7,3',4'-Tetramethoxyflavone	Fungal Parasite Bacterial	Infection
5,7,3',4'-Tetramethoxyflavone, an orally active polymethoxyflavones (PMFs) that can be isolated from M. exotica, possesses various bioactivities, including anti-fungal, anti-malarial, anti-mycobacterial, and anti-inflammatory activities. 5,7,3',4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling .

HY-152035

Mycobacterial Zmp1-IN-1	Bacterial	Infection Inflammation/Immunology
Mycobacterial Zmp1-IN-1 is a mycobacterial zinc metalloprotease-1 (Zmp1) inhibitor. Mycobacterial Zmp1-IN-1 has anti-mycobacterial activity for Mtb H37Ra in dose-dependent inhibition. Mycobacterial Zmp1-IN-1 can be used for the research of tuberculosis (TB) .

HY-148180

Antimycobacterial agent-4	Bacterial Parasite	Infection
Antimycobacterial agent-4 is a 2-amino-4-(2-pyridyl) thiazole derivative, with antimycobacterial activity, antiplasmodial activity, and cytotoxicity on a mammalian cell line .

HY-146104

Antimycobacterial agent-1	Bacterial	Infection
Antimycobacterial agent-1 (compound 33) has selectively antimycobacterial activity against Mycobacterium tuberculosis (M. tuberculosis) H37Ra with a MIC value of 1 μg/ml. Antimycobacterial agent-1 has relatively low cytotoxicity in normal cells (Vero cells IC₅₀ = 143.2 μg/ml) .

HY-76293

I2906

1 Publications Verification

Bacterial Infection

I2906 showed antimycobacterial and cytotoxic activity against mycobacterium tuberculosis.
HY-N9531

3'-Hydroxyxanthyletin

Bacterial Infection

3'-Hydroxyxanthyletin is a coumarin compound with antimycobacterial activities .
HY-N29777

Cabraleahydroxylactone

Parasite Infection

Cabraleahydroxylactone is a dammarane triterpenoid with antimycobacterial activity against Mycobacterium tuberculosis .
HY-N3536

Canthin-6-one

Bacterial Inflammation/Immunology

Canthin-6-one displays a wide range of biological activities, such as antimycobacterial activity .
HY-156361

Tuberculosis inhibitor 11

Bacterial Infection

Tuberculosis inhibitor 11 (Compound 14) can sensitize the antimycobacterial activity of the antitubercular agent .

I2906 1 Publications Verification	Bacterial	Infection
I2906 showed antimycobacterial and cytotoxic activity against mycobacterium tuberculosis.

3'-Hydroxyxanthyletin	Bacterial	Infection
3'-Hydroxyxanthyletin is a coumarin compound with antimycobacterial activities .

Cabraleahydroxylactone	Parasite	Infection
Cabraleahydroxylactone is a dammarane triterpenoid with antimycobacterial activity against Mycobacterium tuberculosis .

Canthin-6-one	Bacterial	Inflammation/Immunology
Canthin-6-one displays a wide range of biological activities, such as antimycobacterial activity .

Tuberculosis inhibitor 11	Bacterial	Infection
Tuberculosis inhibitor 11 (Compound 14) can sensitize the antimycobacterial activity of the antitubercular agent .

HY-N3301

Melilotigenin C	Parasite Bacterial	Infection
Melilotigenin C can be isolated from genus Erythrina. Melilotigenin C can be used for research on antiplasmodial activity, antimycobacterial activity and cytotoxicity .

HY-146487

Anti-infective agent 1	Bacterial Parasite	Infection
Anti-infective agent 1 (compound 3a) is a potent and selective antiprotozoal and antimycobacterial agent. Anti-infective agent 1 shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC₅₀ values of 10.95 and 0.06 μM, respectively. Anti-infective agent 1 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 8 μg/mL .

HY-147884

Antitubercular agent-28	Bacterial	Infection
Antitubercular agent-28 (compound 2) is a potent antitubercular agent with an IC₅₀ value of 1.5 µM, an MIC value of 4.5 µM, an IC₉₀ value of 2.5 µM. Antitubercular agent-28 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv. Antitubercular agent-28 shows effective intracellular antimycobacterial activity and low cytotoxicity .

HY-147883

Antitubercular agent-27	Bacterial	Infection
Antitubercular agent-27 (compound 1) is a potent antitubercular agent with an IC₅₀ value of 3.2 µM, an MIC value of 7.8 µM, an IC₉₀ value of 7.0 µM. Antitubercular agent-27 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv. Antitubercular agent-27 shows effective intracellular antimycobacterial activity and low cytotoxicity .

HY-N9615

Azadiradione	HSP	Infection Neurological Disease Inflammation/Immunology
Azadiradione is a bioactive limonoid found in Azadirachta indica. Azadiradione is a HSF1 activator. Azadiradione has antimycobacterial, anti-nociceptive and anti-inflammatory activities .

HY-N1205

Spathulenol
Spathulenol is isolated from Aristolochia yunnanensis, and has antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities. Spathulenol shows a high antioxidant activity with an IC₅₀ of 85.60 μg/mL in the DPPH system ^[1].

HY-129605

Ferulenol	Oxidative Phosphorylation Mitochondrial Metabolism	Infection
Ferulenol, a sesquiterpene prenylated coumarin derivative, specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Ferulenol shows good antimycobacterial activity and haemorrhagic action .

HY-N2060

Evocarpine	Apoptosis Bacterial	Infection Inflammation/Immunology Cancer
Evocarpine, a quinolone alkaloid that could be isolated from Evodiae fructus, inhibitss Ca ²⁺ influx through voltage-dependent calcium channels. Antimycobacterial activity .

HY-N1160

Tetrahydroxysqualene	Bacterial	Infection
Tetrahydroxysqualene is a triterpene, possessing antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 10.0 μg/mL. Tetrahydroxysqualene can be isolated from the methanolic extracts of Rhus taitensis Guill .

HY-155332

AB131	Bacterial	Infection
AB131 is a MSMEG 6649 and Rv2172c inhibitor (K_d: 0.16 and 0.02 μM respectively). AB131 can sensitize the antimycobacterial activity of the antitubercular agent .

HY-146003

FAAL-IN-1	Bacterial	Infection
FAAL-IN-1 (compound 32) is a selective inhibitor of fatty acyl-AMP ligase (FAAL), with a K_i of 0.7 μM for FAAL28. FAAL-IN-1 shows antimycobacterial activity .

HY-143249

MtMetAP1-IN-1	Bacterial	Infection
MtMetAP1-IN-1 is an inhibitor of Mycobacterium tuberculosis (Mtb), targeting methionine aminopeptidase 1 (MetAP1). MtMetAP1-IN-1 exerts antimycobacterial activity .

HY-141715

BRD-8000.3	Antibiotic	Infection
BRD-8000.3, as a specific EfpA inhibitor, is a narrow-spectrum, bactericidal antimycobacterial agent with good wild-type activity. BRD-8000.3 can be used for the research of tuberculosis .

HY-G0016

N-Acetyl dapsone MADDS; Monoacetyldapsone	Drug Metabolite	Others
N-Acetyl dapsone (MADDS) is the major metabolite of Dapsone (HY-B0688). Dapsone is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities .

HY-162028

GaMF1.39	Bacterial	Infection
GaMF1.39 is an *antimycobacterial* compound, targeting the F-ATP synthase subunit γ. GaMF1.39 displays enhanced anti-tuberculosis activity in combination with ETC inhibitors .

HY-N6005

Methyl caffeate	Bacterial	Infection Cancer
Methyl caffeate, an antimicrobial agent, shows moderate antimicrobial and prominent antimycobacterial activities. Methyl caffeate also exhibits α-glucosidase inhibition activity, oxidative stress inhibiting activity, anti-platelet activity, antiproliferative activity in cervix adenocarcinoma and anticancer activity in lung and leukmia cell lines .

HY-149857

Antitubercular agent-37	Bacterial	Infection
Antitubercular agent-37 is an antibacterial agent. Antitubercular agent-37 has antimycobacterial activity with an MIC values of 0.16 μg/mL. Antitubercular agent-37 can be used for the research of tuberculosis .

HY-N11646

Ganorbiformin B	Bacterial	Infection
Ganorbiformin B is a lanostane triterpenoid. Ganorbiformin B shares the same lanostane skeleton with known ganoderic acids. The C-3 epimer of ganoderic acid T exhibits potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra .

HY-146489

Anti-infective agent 3	Bacterial Parasite	Infection
Anti-infective agent 3 (compound 3l) shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC₅₀ values of 0.47 and 0.13 μM, respectively. Anti-infective agent 3 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 4 μg/mL .

HY-115900

Tuberculosis inhibitor 4	Bacterial	Infection
Tuberculosis inhibitor 4 (compound 16), a mandelic acid-based spirothiazolidinone, has potent *antimycobacterial* activity against Mycobacterium tuberculosis strain H37Rv with the high inhibition value 98% at lower than 6.25 µg/mL concentration .

HY-149347

Mtb-IN-3	Bacterial	Infection
Mtb-IN-3 (compound 10c) is an inhibitor of Mycobacterium tuberculosis (Mtb). Mtb-IN-3 shows selective, potent in vitro antimycobacterial activity without cytotoxicity. Mtb-IN-3 inhibits colony-forming in spleen in the murine tuberculosis model .

HY-146488

Anti-infective agent 2	Parasite Bacterial	Infection
Anti-infective agent 2 (compound 3k) shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC₅₀ values of 0.07 and 2.20 μM, respectively. Anti-infective agent 2 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 32 μg/mL .

HY-W012875

3-Nitropropanoic acid β-Nitropropionic acid; Bovinocidin	Bacterial Apoptosis Autophagy	Infection Metabolic Disease
3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible and orally active inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM. 3-Nitropropanoic acid can induce cell apoptosis .

HY-133671S

Monooctyl phthalate-d4 Mono-n-octyl phthalate-d₄	Isotope-Labeled Compounds	Infection
Monooctyl phthalate-d₄ (Mono-n-octyl phthalate-d₄) is a deuterium labeled Monooctyl phthalate (HY-133671). Monooctyl phthalate (Mono-n-octyl phthalate) exhibits antimycobacterial activity with a MIC of 20 μg/mL .

HY-N2277

3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone	Bacterial	Infection Inflammation/Immunology
3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone is a natural compound that could be isolated from G. lucidum with antimycobacterial activity.

HY-100725

BM212 3 Publications Verification	Bacterial	Infection
BM212 is a potent Mycobacterial membrane protein Large 3 (MmpL3) inhibitor. BM212 has strong bactericidal activity against both M. tuberculosis and some nontuberculosis mycobacteria. BM212 exhibits antimycobacterial activity against M. tuberculosis H37Rv with an MIC of 5 µM .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8131

Pangelin	Infection other families Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Disease Research Fields	Bacterial
Pangelin is a coumarin that can be found in Ducrosia anethifolia. Pangelin exhibits anti-mycobacterial and anti-tumor activities .

HY-N3845

Ergosterol peroxide	Natural Products Classification of Application Fields Orchidaceae Source classification Plants Disease Research Fields Inflammation/Immunology Anoectochilus elwesii	Bacterial
Ergosterol peroxide is a steroid derivative and can be isolated from a variety of fungi, yeast, lichens or sponges. Ergosterol peroxide has anti-tumour, proapoptotic, anti-inflammatory, anti-mycobacterial, and anti-proliferative activities .

HY-N2443

Tribuloside 1 Publications Verification	Tribulus terrester Linn. Flavonols Flavonoids Zygophyllaceae Source classification Phenols Polyphenols Plants	Bacterial
Tribuloside is a flavonoid that can be isolated from Tribulus terrestris L . Tribuloside exhibits *anti-mycobacterial* activity against the non-pathogenic Mycobacterium species with a minimum inhibitory concentration (MIC) of 5.0 mg/mL. Tribuloside has 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity .

HY-N7030

5,7,3',4'-Tetramethoxyflavone	Infection Structural Classification Flavonoids Classification of Application Fields Flavones Source classification Rutaceae Plants Disease Research Fields Murraya exotica L. Mant.	Fungal Parasite Bacterial
5,7,3',4'-Tetramethoxyflavone, an orally active polymethoxyflavones (PMFs) that can be isolated from M. exotica, possesses various bioactivities, including anti-fungal, anti-malarial, anti-mycobacterial, and anti-inflammatory activities. 5,7,3',4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling .

HY-N9531

3'-Hydroxyxanthyletin	Infection other families Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Disease Research Fields	Bacterial
3'-Hydroxyxanthyletin is a coumarin compound with antimycobacterial activities .

HY-N29777

Cabraleahydroxylactone	Triterpenes Structural Classification Terpenoids Chisocheton penduliflorus Planch. ex Hiern Source classification Plants Meliaceae	Parasite
Cabraleahydroxylactone is a dammarane triterpenoid with antimycobacterial activity against Mycobacterium tuberculosis .

HY-N3536

Canthin-6-one	Alkaloids Structural Classification Classification of Application Fields Source classification Rutaceae Quinoline Alkaloids Plants Inflammation/Immunology Disease Research Fields Zanthoxylum stenophyllum Hemsl. Indole Alkaloids	Bacterial
Canthin-6-one displays a wide range of biological activities, such as antimycobacterial activity .

HY-N3301

Melilotigenin C	Structural Classification Natural Products Leguminosae Source classification Erythrina stricta Roxb. Plants	Parasite Bacterial
Melilotigenin C can be isolated from genus Erythrina. Melilotigenin C can be used for research on antiplasmodial activity, antimycobacterial activity and cytotoxicity .

HY-N9615

Azadiradione	Triterpenes other families Neurological Disease Classification of Application Fields Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields Biological Pesticide Research Agricultural Research	HSP
Azadiradione is a bioactive limonoid found in Azadirachta indica. Azadiradione is a HSF1 activator. Azadiradione has antimycobacterial, anti-nociceptive and anti-inflammatory activities .

HY-129605

Ferulenol	Infection Structural Classification other families Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Disease Research Fields	Oxidative Phosphorylation Mitochondrial Metabolism
Ferulenol, a sesquiterpene prenylated coumarin derivative, specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Ferulenol shows good antimycobacterial activity and haemorrhagic action .

HY-N2060

Evocarpine	Infection Alkaloids Classification of Application Fields Source classification Evodia rutaecarpa (Juss.) Benth. Rutaceae Quinoline Alkaloids Plants Disease Research Fields Inflammation/Immunology	Apoptosis Bacterial
Evocarpine, a quinolone alkaloid that could be isolated from Evodiae fructus, inhibitss Ca ²⁺ influx through voltage-dependent calcium channels. Antimycobacterial activity .

HY-N1160

Tetrahydroxysqualene	Infection Triterpenes Rhus taitensis Guill. Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Anacardiaceae	Bacterial
Tetrahydroxysqualene is a triterpene, possessing antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 10.0 μg/mL. Tetrahydroxysqualene can be isolated from the methanolic extracts of Rhus taitensis Guill .

HY-N6005

Methyl caffeate	Infection Classification of Application Fields Simple Phenylpropanols Source classification Phenols Polyphenols Solanum torvum Swartz Phenylpropanoids Plants Solanaceae Disease Research Fields	Bacterial
Methyl caffeate, an antimicrobial agent, shows moderate antimicrobial and prominent antimycobacterial activities. Methyl caffeate also exhibits α-glucosidase inhibition activity, oxidative stress inhibiting activity, anti-platelet activity, antiproliferative activity in cervix adenocarcinoma and anticancer activity in lung and leukmia cell lines .

HY-N11646

Ganorbiformin B	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	Bacterial
Ganorbiformin B is a lanostane triterpenoid. Ganorbiformin B shares the same lanostane skeleton with known ganoderic acids. The C-3 epimer of ganoderic acid T exhibits potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra .

HY-W012875

3-Nitropropanoic acid β-Nitropropionic acid; Bovinocidin	Structural Classification Microorganisms other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Plants Disease Research Fields	Bacterial Apoptosis Autophagy
3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible and orally active inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM. 3-Nitropropanoic acid can induce cell apoptosis .

HY-N2277

3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone	Natural Products Classification of Application Fields Source classification Polyporaceae Plants Disease Research Fields Inflammation/Immunology	Bacterial
3β,7β,15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone is a natural compound that could be isolated from G. lucidum with antimycobacterial activity.

HY-N11048

Amycolatopsin A	Infection Structural Classification Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields Cancer	Bacterial
Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows **antimycobacterial activity** against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC₅₀ values of 0.4 µM and 4.4 µM, respectively .

HY-W001663

4'-Hydroxy-3'-methylacetophenone	Infection Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Rubiaceae Phenols Plants Disease Research Fields Coffea arabica L.	Bacterial
4'-Hydroxy-3'-methylacetophenone, a phenolic volatile compound, is isolated from Hawaiian green coffee beans (Coffea Arabica L.). 4'-Hydroxy-3'-methylacetophenone has potent antioxidant activities. 4'-Hydroxy-3'-methylacetophenone also can be used to synthesize heterocyclic compounds which have antimycobacterial activity .

HY-N0941

beta-Mangostin 1 Publications Verification β-Mangostin	Infection Xanthones Classification of Application Fields Source classification Guttiferae Phenols Polyphenols Garcinia mangostana Linn. Plants Disease Research Fields Cancer	Bacterial Parasite Apoptosis
beta-Mangostin (β-Mangostin) is a xanthone compound present in Cratoxylum arborescens, with antibacterial and antimalarial activities. beta-Mangostin exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. beta-Mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC₅₀ of 3.00 μg/mL. beta-Mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic) .

Cat. No.	Product Name	Chemical Structure

HY-133671S

Monooctyl phthalate-d4
Monooctyl phthalate-d₄ (Mono-n-octyl phthalate-d₄) is a deuterium labeled Monooctyl phthalate (HY-133671). Monooctyl phthalate (Mono-n-octyl phthalate) exhibits antimycobacterial activity with a MIC of 20 μg/mL .

HY-B0688S1

Dapsone-d4

Dapsone-d₄ is the deuterium labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities[1]. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al[2][3].

HY-B0688S2

Dapsone-13C12

Dapsone- ¹³C₁₂ is the ¹³C₁₂ labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

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